Genetic screening: implications for preventive medicine.

Screening for familial hypercholesterolemia: a model for preventive medicine.

The most common genetic cause of premature coronary artery disease (CAD) is familial hypercholesterolemia (FH), an autosomal dominant condition in which half the offspring of an affected individual will also be affected from birth. The causative mutations are mainly found in the LDL receptor gene (LDLR) and less frequently in the apolipoprotein B gene and the proprotein subtilisin/kexin type 9 ...

The ethical implications of screening for HIV: whose choice reigns?

Preventive Medicine

Background. The purpose of this study was to evaluate the association between receptivity to cigarette promotions and smoking uptake in a cohort of adolescents. Methods and Measures. This was a prospective cohort study of 480 4thto 11th-grade students conducted in three rural Vermont K–12 schools. Cigarette use was determined by self-report at baseline, 12 months (survey 2), and 21 months (surv...

Preventive Medicine

Background. African Americans have low immunization rates, yet little is known about their immunization knowledge, attitudes, and practices or about the effect of outreach to this audience. In Spring 1997, the California Department of Health Services (CDHS) launched a statewide culturally sensitive and ethnically specific media campaign directed toward African Americans. This campaign was prece...

Preventive Medicine